Usually, I would leave someone else to answer, but seeing as no one has, this is my first time posting. I apologize if I say something wrong.
I'm not sure where you are in the game, but from the lack of many Servants, I assume you are somewhere near the beginning. Sorry if you already know some of the stuff below.
You could just bring all three of them (or switch Mordred for Tamamo Cat) to get a Buster team, which can carry you through the easy content. This strategy won't work for harder content though...
Heracles is a finisher - you would usually want to put him at the end of the team, so he can finish off anything. Not sure if he would fit in the front line - I've only ever done so when using a Buster team.
Lancelot will often do more single-target damage than Mordred through critical buster hits, but is also obviously more fragile. If you use Lancelot to do damage, you can also use Leonidas and Hassan/Sasaki in your front row - their quicks generate stars, which Lancelot will abuse, while Leonidas will also cover for Lancelot. Avoid using riders (and to a lesser extent, archers) in this setup, because they will steal stars from Lancelot. Martha and Robin aren't good critters anyways. Unfortunately, there aren't a whole lot of quick-based defensive Servants, so instead of defensive options, offensive Servants like Caesar and Ushi can help burst down enemies (keep an eye out for them). Note that this strategy pretty much gives up on using Lancelot's NP.
Mordred is built around NP spam. If you use Mordred as your damager, you should use arts Servants to help her spam her NP (and to hopefully protect/buff her as well). You may also use Robin Hood as your damager instead, because his NP hits very hard when overcharged (and hits harder if buffed - Mozart). If you follow this strategy, look out for Hans and Georgios to add to the team as supports.
Still, as you progress through the game, feel free to create new teams as you gather more Servants. Note that I have not taken into account Craft Essences - if you think you can ignore some of the advice because a craft essence (Fragment of 2030 and Seal Designation Enforcer are examples) or a new Servant changes the situation, feel free.
Edit: This turned out really long... sorry!
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